| 引用本文: |
徐梦娇, 汪伟, 刘惠梅, 王彬, 高峰.基于痰瘀同治理论探讨慢性阻塞性肺疾病急性加重高凝状态的辨治[J].湖南中医药大学学报,2024,44(11):2131-2135[点击复制] |
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| 基于痰瘀同治理论探讨慢性阻塞性肺疾病急性加重高凝状态的辨治 |
| 徐梦娇,汪伟,刘惠梅,王彬,高峰 |
| (中国中医科学院望京医院, 北京 100000) |
| 摘要: |
| 以“痰瘀同治”理论为基础并结合临床验案，探析慢性阻塞性肺疾病急性加重（acute exacerbation of chronic obstructive pulmonary disease, AECOPD）高凝状态的病机与治则，认为“因痰致瘀，痰瘀互结”是AECOPD高凝状态的病机关键，即痰是其始动因素，瘀是其继发产物，是因痰致瘀而后又痰瘀互结的病理改变。治疗上既要重视痰之本，也要兼顾血瘀，以活血辅助祛痰，以化痰达祛瘀之功。如此“痰瘀同治”可有效缓解患者临床症状，预防血栓性疾病的发生。 |
| 关键词: 慢性阻塞性肺疾病急性加重 高凝状态 痰瘀同治 活血 化痰 祛瘀 验案 |
| DOI：10.3969/j.issn.1674－070X.2024.11.029 |
| 投稿时间：2024-04-01 |
| 基金项目:中国中医科学院科技创新工程资助项目（CI2021A01102）。 |
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| Differentiation and treatment of hypercoagulable state in acute exacerbation of chronic obstructive pulmonary disease based on the theory of "simultaneous treatment of phlegm and blood stasis" |
| XU Mengjiao, WANG Wei, LIU Huimei, WANG Bin, GAO Feng |
| (Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100000, China) |
| Abstract: |
| Based on the theory of "simultaneous treatment of phlegm and blood stasis", this paper explores the pathogenesis and treatment principles of hypercoagulable state in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with a verified clinical medical record. It is proposed that "the formation of phlegm leading to blood stasis, subsequently causing the intermingling of phlegm and static blood" is the key pathogenesis underlying the hypercoagulable state in AECOPD, wherein phlegm serves as the initiating factor and static blood as the secondary product. Both phlegm and blood stasis represent the pathological changes in this process. Accordingly, treatment should address both the root cause of phlegm and the accompanying blood stasis, using blood-circulating methods to assist in eliminating phlegm, and phlegm-transforming methods to facilitate resolving blood stasis. This approach of "treating phlegm and blood stasis simultaneously" can effectively alleviate clinical symptoms and prevent thrombotic diseases in patients. |
| Key words: acute exacerbation of chronic obstructive pulmonary disease hypercoagulable state simultaneous treatment of phlegm and blood stasis circulating blood transforming phlegm resolving blood stasis a verified medical record |
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