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周小钰, 李方芳, 刘倩宏, 姚小磊.青光眼滤过术后抗瘢痕化的研究进展[J].湖南中医药大学学报,2024,44(7):1328-1334[点击复制] |
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| 青光眼滤过术后抗瘢痕化的研究进展 |
| 周小钰,李方芳,刘倩宏,姚小磊 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007;中医药防治眼耳鼻咽喉疾病湖南省重点实验室, 湖南 长沙 410208) |
| 摘要: |
| 青光眼的典型表现是病理性眼压升高，手术疗法是一种迅速降低眼压的治疗手段。而青光眼滤过手术的成功率与术后抗瘢痕化有密切关系，术后抗瘢痕化成为提高青光眼手术成功率的重要议题。除了传统的抗代谢药物，目前已有新型抗代谢药物、新型分子生物材料、基因材料等，中医药同时也在抗瘢痕化方面有所研究。本文对近年来青光眼滤过术后的抗瘢痕化研究进行综述。 |
| 关键词: 青光眼 抗瘢痕化 青光眼滤过手术 成纤维细胞 抗血管内皮生长因子药物 中药 |
| DOI：10.3969/j.issn.1674-070X.2024.07.028 |
| 投稿时间：2023-07-29 |
| 基金项目:湖南省“芙蓉学者”奖励计划（湘人才办〔2022〕3号）；湖南中医药大学“王衡新科研基金”项目（2023HX007）；湖南省研究生科研创新项目（2023CX45）；湖南省卫生健康委员会高层次人才计划（2022年）。 |
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| Research progress on anti-scarring after glaucoma filtration surgery |
| ZHOU Xiaoyu, LI Fangfang, LIU Qianhong, YAO Xiaolei |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan Key Laboratory of TCM Prevention and Treatment of Eye, Ear, Nose and Throat diseases, Changsha, Hunan 410208, China) |
| Abstract: |
| The typical manifestation of glaucoma is characterized by a pathological increase in intraocular pressure, and surgical treatment serves as a means of rapidly reducing it. The success rate of glaucoma filtration surgery is closely linked to postoperative anti-scarring, making anti-scarring an important factor in enhancing the success rate of glaucoma surgery. In addition to traditional anti-metabolic drugs, there are also novel anti-metabolic drugs, new molecular biomaterials, genetic materials, etc. At the same time, Chinese medicine has also delved into the study of anti-scar drugs. This paper reviews the recent research on anti-scarring for glaucoma filtration surgery. |
| Key words: glaucoma anti-scarring glaucoma filtration surgery fibroblast anti-vascular endothelial growth factor drugs Chinese medicines |
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