| 引用本文: |
彭田甜, 尹抗抗, 黎鹏程.从伏邪理论探讨非酒精性脂肪性肝病的“多次打击”病机[J].湖南中医药大学学报,2024,44(6):1074-1078[点击复制] |
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| 从伏邪理论探讨非酒精性脂肪性肝病的“多次打击”病机 |
| 彭田甜,尹抗抗,黎鹏程 |
| (湖南中医药大学中医学院, 湖南 长沙 410208;湖南中医药大学资产与实验室管理处, 湖南 长沙 410208) |
| 摘要: |
| 非酒精性脂肪性肝病是临床常见的代谢性肝脏疾病，后期常引起肝硬化和“炎—癌”转化。本病存在不同时空下多重病因叠加损伤的“多次打击”，这种“多次打击”效应符合中医伏邪致病理论的特点。其中，伏痰、伏瘀、伏毒留滞体内，渐进渐聚，阻于肝络；伏邪作乱，造成肝络损伤。因此，在治疗上祛除体内伏痰、伏瘀、伏毒可有效避免非酒精性脂肪性肝病的“多次打击”，以期为临床提供新的治疗思路。 |
| 关键词: 非酒精性脂肪性肝病 伏痰 伏瘀 伏毒 多次打击 |
| DOI：10.3969/j.issn.1674-070X.2024.06.020 |
| 投稿时间：2023-11-29 |
| 基金项目:湖南省自然科学基金项目（2022JJ30446）；湖南省教育厅科学研究项目（21B0393）；湖南省中医药管理局重点项目（201208）。 |
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| Multi-hit pathogenesis of nonalcoholic fatty liver disease based on the theory of latent pathogenic qi |
| PENG Tiantian, YIN Kangkang, LI Pengcheng |
| (School of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Office of Asset and Laboratory Management, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Nonalcoholic fatty liver disease (NAFLD) is a common metabolic liver disease in clinic, which often causes liver cirrhosis and "inflammation-cancer" transformation in the later stage. The disease is characterized by "multi-hit" of superimposed injuries of multiple pathogenic factors across different time and spaces, and this "multi-hit" effect is in line with the characteristics of the TCM theory of "latent pathogenic qi causing disease". That is, the latent phlegm, blood stasis, and toxins remain in the body, gradually accumulating and blocking the liver collaterals, or damaging them. Therefore, it is believed that the removal of latent phlegm, blood stasis, and toxins in the body can effectively prevent the "multi-hit" associated with NAFLD. This paper aims to provide new treatment ideas for clinical practice. |
| Key words: nonalcoholic fatty liver disease latent phlegm latent blood stasis latent toxins multi-hit |
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