| 引用本文: |
刘莉婷,刘建和.基于数据挖掘探索慢性心力衰竭伴利尿剂抵抗中医诊疗特点[J].湖南中医药大学学报,2024,44(1):101-107[点击复制] |
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| 基于数据挖掘探索慢性心力衰竭伴利尿剂抵抗中医诊疗特点 |
| 刘莉婷,刘建和 |
| (湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学第一附属医院, 湖南 长沙 410007;国家中医心血管临床医学研究中心分中心, 湖南 长沙 410007) |
| 摘要: |
| 目的 针对《慢性心力衰竭伴利尿剂抵抗中医诊疗方案》课题组的设计要求，对相关中医证型、治法及方药的制定进行调研。方法 计算机检索PubMed、EMbase、中国知网、万方和维普数据库2000年1月至2023年7月在国内公开期刊公开发表的与慢性心力衰竭（chronic heart failure， CHF）伴利尿剂抵抗（diuretic resistance， DR）相关的文献，对所涉及的证型、治法及用药频率、频次进行归类统计分析。结果 在所检索的符合纳入标准的42篇现代中文文献中，CHF伴DR的中医证型多以气虚血瘀、阳虚水泛证及心肾阳虚证为主；治法要素多以利水、活血、温阳、益气为主；治疗上多数学者偏好用真武汤进行加减论治；药物选择上以补虚药、利水渗湿药居多；治疗CHF伴DR的高频中药药性以温、寒、平为主；药味以甘、辛、苦为主；归经以脾经、肺经居多。结论 通过文献研究探索出CHF伴DR的相关中医证型及治法方药的特点，可为后续中医诊疗方案的制定提供参考。 |
| 关键词: 慢性心力衰竭 利尿剂抵抗 中医 诊疗方案 数据挖掘 |
| DOI：10.3969/j.issn.1674-070X.2024.01.015 |
| 投稿时间：2023-09-06 |
| 基金项目:湖南省中医药管理局科研计划重点项目（D2023005，2021011）；湖南省教育厅科学研究重点项目（21A0234）；中医学湖南省世界一流培育学科（湘教发〔2022〕57号）。 |
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| TCM diagnosis and treatment characteristics of chronic heart failure with diuretic resistance based on data mining |
| LIU Liting,LIU Jianhe |
| (The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Sub-center of National Clinical Research Center for Cardiovascular Diseases of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To investigate the development of relevant TCM pattern types, treatment methods, and medicines and formulas in response to the design requirements of "Chinese Medicine Diagnosis and Treatment Plan for Chronic Heart Failure(CHF) with Diuretic Resistance (DR)" research group. Methods The literature related to CHF with DR published in domestic public journals from January 2000 to July 2023 were screened in PubMed, EMbase, CNKI, Wanfang and VIP databases. Then, the pattern types, treatment methods, medication frequency, and the number of medication occurrence were classified and statistically analyzed. Results The 42 modern Chinese papers that met the inclusion criteria showed the following characteristics:the TCM pattern types of CHF with DR were mainly qi deficiency induced blood stasis, yang deficiency induced water retention, and yang deficiency of the heart and kidney patterns; the main treatment methods included promoting urination, circulating blood, warming yang, and tonifying qi; in terms of medication, many academics preferred to use modified Zhenwu Decoction, and tonic medicines and urination-promoting and dampness-draining medicines were mainly taken; the high-frequently used Chinese medicines were mainly warm, cold, and neutral in property, and sweet, pungent, and bitter in flavor, mostly entering the spleen and lung meridians. Conclusion This article has explored the characteristics of relevant TCM pattern types, treatment methods, and medicines and formulas for CHF with DR through literature research, which can provide reference for subsequent formulation of TCM diagnosis and treatment plans. |
| Key words: chronic heart failure diuretic resistance Chinese medicine diagnosis and treatment plan data mining |
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