| 引用本文: |
刘同心,岳铭坤,夏宇,周良荣.针灸治疗带状疱疹的临床疗效及安全性系统评价和Meta分析[J].湖南中医药大学学报,2022,42(5):800-808[点击复制] |
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| 针灸治疗带状疱疹的临床疗效及安全性系统评价和Meta分析 |
| 刘同心,岳铭坤,夏宇,周良荣 |
| (湖南中医药大学人文与管理学院, 湖南 长沙 410208;湖南中医药大学中医学院, 湖南 长沙 410208) |
| 摘要: |
| 目的 系统评估针灸治疗带状疱疹的临床疗效及安全性。方法 检索中国知网、万方学术期刊全文数据库、重庆维普期刊全文数据库、中国生物医学文献数据库、PubMed数据库自建库以来至2021年12月18日发表的针灸治疗带状疱疹的临床随机对照试验。以患者总有效率、疼痛评价、并发症、安全性评价作为结局指标。根据Cochrane偏倚风险评估标准对文献质量进行评价，由两名研究者进行文献筛选，并使用RevMan 5.3软件进行Meta分析。结果 最终共纳入43篇文献，3381例患者纳入本研究，试验组1750例，对照组1631例。Meta分析表明：与抗病毒等西医常规治疗比较，针灸治疗显著提高了患者总有效率（OR=4.20，P<0.000 01）；缓解了疼痛，例如降低了疼痛评分（MD=-1.44，P<0.000 01），减轻了疼痛强度（MD=1.39，P<0.000 01）；减少了不良反应事件（OR=0.16，P=0.01）；降低了并发症发生率，如降低了30 d（OR=0.18，P=0.26）、60 d（OR=0.27，P=0.99）、90 d（OR=0.28，P=0.98）后遗神经痛发生率。结论 针灸治疗带状疱疹的临床疗效优于西医治疗，在今后的临床治疗中可考虑采用针灸治疗。 |
| 关键词: 中医 针灸 西医治疗 带状疱疹 Meta分析 |
| DOI：10.3969/j.issn.1674-070X.2022.05.018 |
| 投稿时间：2022-01-18 |
| 基金项目:湖南省教育厅科学研究重点项目（21A0251）。 |
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| Clinical efficacy and safety of acupuncture in the treatment of herpes zoster: A system review and meta-analysis |
| LIU Tongxin,YUE Mingkun,XIA Yu,ZHOU Liangrong |
| (College of Humanities and Management, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To systematically evaluate the clinical efficacy and safety of acupuncture in the treatment of herpes zoster. Methods Randomized controlled clinical trials of acupuncture in the treatment of herpes zoster were retrieved from China National Knowledge Infrastructure (CNKI), Wan-Fang Database, Chinese Scientific Journal Database (VIP database), the Chinese Biomedical Literature Database (CBM), and PubMed from its establishment to December 18, 2021. Total effective rate, pain evaluation, complications and safety evaluation were used as outcome indexes. Literature quality was evaluated according to the bias risk assessment criteria of Cochrane, literature selection was conducted by two investigators, and meta-analysis was performed using RevMan 5.3 software. Results A total of 43 articles with 3381 patients were contained in the study, including 1750 in the treatment group and 1631 in the control group. Meta-analysis showed that compared with conventional treatment in western medicine such as antiviral therapy, acupuncture treatment remarkably improved the patients' total effective rate (OR=4.20, P<0.000 01); relieved the pain:decreased pain scores (MD=-1.44, P<0.000 01), reduced pain intensity (MD=1.39, P<0.000 01); decreased adverse events (OR=0.16, P=0.01). The incidence of complications was reduced, for example, the incidence of residual neuralgia after 30 days (OR=0.18, P=0.26), 60 days (OR=0.27, P=0.99), 90 days (OR=0.28, P=0.98). Conclusion The therapeutic effect of acupuncture on herpes zoster is better than that of western medicine, so it can be considered in the future clinical treatment. |
| Key words: traditional Chinese medicine acupuncture western medicine treatment herpes zoster meta-analysis |
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