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肖瑾,韦春玲,肖珊,罗姣,卢茂芳,鲁曼霞,刘向前.糙叶五加化学成分及其生物活性研究进展[J].湖南中医药大学学报,2021,41(8):1297-1306[点击复制] |
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| 糙叶五加化学成分及其生物活性研究进展 |
| 肖瑾,韦春玲,肖珊,罗姣,卢茂芳,鲁曼霞,刘向前 |
| (湖南中医药大学 药学院, 湖南 长沙 410208) |
| 摘要: |
| 糙叶五加是五加科五加属植物，具有祛风湿、补肝肾、活血化瘀、壮筋骨等功效，主要用于治疗风湿痹痛、拘挛麻木、筋骨痞软、水肿、跌打损伤、疝气腹痛等。糙叶五加的化学成分主要为黄酮类、萜类、苯丙素类、有机酸类、甾体类、蒽醌类等，具有抗炎、抗菌、抑制胆碱酯酶等多种生物活性。文中主要对糙叶五加的化学成分及生物活性进行综述，为糙叶五加的进一步研究和开发提供一定的理论基础。 |
| 关键词: 糙叶五加 化学成分 生物活性 抗炎 抗神经炎 抗菌 抑制胆碱酯酶 |
| DOI：10.3969/j.issn.1674-070X.2021.08.029 |
| 投稿时间：2021-01-16 |
| 基金项目:湖南省自然科学基金项目（2019JJ40223，2019JJ50448）；湖南中医药大学生物工程重点学科项目（校行科字[2018]3号）。 |
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| Advance on Chemical Constituents and Bioactivity of Acanthopanax Henryi (Oliv.) Harms |
| XIAO Jin,WEI Chunling,XIAO Shan,LUO Jiao,LU Maofang,LU Manxia,LIU Xiangqian |
| (School of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Acanthopanax henryi (Oliv.) Harms is a plant belonging to Acanthopanax senticosus in Acanthopanax family. Acanthopanax henryi (Oliv.) Harms has the effects of eliminating wind dampness, tonifying liver and kidney, promoting blood circulation and removing blood stasis, strengthening muscles and bones. It is mainly used to treat rheumatic arthralgia, contracture numbness, soft muscles and bones, edema, traumatic injury, hernia and abdominal pain, etc. The main chemical components are flavonoids, terpenes, phenylpropanoids, organic acids, steroids, anthraquinones, etc. It has many biological activities such as anti-inflammatory, anti-bacterial and anti-cholinesterase. In this paper, we made a review on the chemical components and biological activity of Acanthopanax henryi (Oliv.) Harms, which can provide a theoretical basis for its further research and development. |
| Key words: Acanthopanax henryi (Oliv.) Harms chemical component biological activity anti-inflammatory anti-neuroinflammation anti-bacterial anti-cholinesterase |
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