| 引用本文: |
狄奇,谢晓,谢海平,蒋斌,蒋伟平,贺潇,刘起立,蔡蔚.芪金合剂联合硕通镜治疗上尿路结石的疗效及安全性研究[J].湖南中医药大学学报,2021,41(7):1110-1114[点击复制] |
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| 芪金合剂联合硕通镜治疗上尿路结石的疗效及安全性研究 |
| 狄奇,谢晓,谢海平,蒋斌,蒋伟平,贺潇,刘起立,蔡蔚 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007) |
| 摘要: |
| 目的 探讨芪金合剂联合硕通镜治疗上尿路结石的有效性与安全性。方法 将80例输尿管上段结石或肾结石需行硕通镜治疗的患者，随机分为综合治疗组与单纯手术组，每组40例，单纯手术组术后仅对症治疗，综合治疗组在单纯治疗组基础上加用芪金合剂治疗。观察两组术后残石排出情况、术后住院时间及术后疼痛视觉模拟评分法（visual analogue scale，VAS）评分、术后尿常规中红细胞及白细胞计数。结果 综合治疗组术后1月结石清除率较单纯手术组高（P<0.05）；综合治疗组术后住院时间、术后1月疼痛VAS评分均低于单纯手术组（P<0.05）；术后1月两组复查尿常规，综合治疗组尿红细胞及白细胞计数低于单纯手术组（P<0.05）。结论 硕通镜术后服用芪金合剂有缩短住院时间、促进残石排出、降低疼痛、血尿等不良反应发生的作用。疗效显著且无明显不良反应，值得临床推广使用及深入研究。 |
| 关键词: 芪金合剂 硕通镜 碎石术 上尿路结石 石淋 |
| DOI：10.3969/j.issn.1674-070X.2021.07.024 |
| 投稿时间：2020-10-11 |
| 基金项目:湖南省科技创新计划项目（2018SK51206）；湖南中医药大学校级科研基金项目（2018XJJJ57）；湖南省教育科学规划课题项目（XJK015BGD049）；湖南省教育厅科学研究项目（2019C1415）。 |
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| Efficacy and Safety on Upper Urinary Calculi by Qijin Mixture Combined with Shuo Tong Ureteroscopy |
| DI Qi,XIE Xiao,XIE Haiping,JIANG Bin,JIANG Weiping,HE Xiao,LIU Qili,CAI Wei |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China) |
| Abstract: |
| Objective To investigate the efficacy and safety of Qijin Mixture combined with Shuo Tong ureteroscopy in the treatment of upper urinary tract stones. Methods 80 cases of upper ureteral calculi or renal calculi who needed Shuo Tong ureteroscopy treatment were randomly divided into comprehensive treatment group and simple operation group, with 40 patients in each group. The simple operation group only received symptomatic treatment after operation, while the comprehensive treatment group was treated with Qijin Mixture on the basis of simple operation group. The postoperative residual stone discharge, postoperative hospital stay, visual analogue scale (VAS) pain score and the number of red blood cells and white blood cells in urine routine were observed in both groups. Results The stone clearance rate of the comprehensive treatment group was higher than that of the simple operation group (P<0.05); the postoperative hospital stay and VAS pain score of the comprehensive treatment group were lower than those of the simple operation group (P<0.05); one month after operation, the total number of urine red blood cells and white blood cells in the urine routine examination in comprehensive treatment group was lower than that of the simple operation group (P<0.05). Conclusion The use of Qijin Mixture after Shuo Tong ureteroscopy can shorten hospitalization time, promote residual stone discharge, reduce pain, hematuria and other adverse reactions. The curative effect is significant and there is no obvious side effect, which is worthy of clinical application and in-depth study. |
| Key words: Qijin Mixture Shuo Tong ureteroscopy lithotripsy upper urinary tract stone urolithiasis |
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