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李翔,邓颖,李新宇,廖林丽,彭清华.2型糖尿病眼底体征与中医证素的相关性研究[J].湖南中医药大学学报,2021,41(7):1073-1078[点击复制] |
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| 2型糖尿病眼底体征与中医证素的相关性研究 |
| 李翔,邓颖,李新宇,廖林丽,彭清华 |
| (湖南中医药大学, 湖南 长沙 410208;湖南中医药大学中医药防治眼耳鼻喉疾病湖南省重点实验室, 湖南 长沙 410208;湖南省中医药防治眼耳鼻咽喉疾病与视功能保护工程技术研究中心, 湖南 长沙 410208) |
| 摘要: |
| 目的 分析2型糖尿病（diabetes mellitus type 2，T2DM）患者的眼底体征与中医证素之间的相关性。方法 通过横断面调查、现场问卷的方式，收集T2DM患者的一般资料、中医症状，包括眼底照相图片与光学相干断层成像（optical coherence tomography，OCT）图片，借助WF文锋-Ⅲ中医（辅助）诊疗系统提取证素，利用关联规则分析中医证素与眼底体征的关系。结果 弥漫性水肿与"湿""湿and肝"的关联性最高，囊样水肿与"气虚and肾and肝"关联性最高；硬性渗出与"气虚and肝"的关联性最高，其次是"湿"；出血以及微血管瘤的关联性最高的证素是"气虚and肾and肝"；黄斑前膜与"阳虚"关联程度最高，其次是"阳虚and肝""阳虚and肾"。结论 眼底体征与某些证素之间有关联：水肿与气虚血瘀水停相关，渗出与气虚湿聚痰凝相关，微血管瘤以及出血与气虚血瘀相关，黄斑前膜与肾阳虚衰相关。 |
| 关键词: 2型糖尿病 糖尿病视网膜病变 眼底体征 中医证素 |
| DOI：10.3969/j.issn.1674-070X.2021.07.017 |
| 投稿时间：2021-02-06 |
| 基金项目:湖南中医药大学中医学国内一流建设学科（湘教通[2018]469号）；中医药防治眼耳鼻喉疾病湖南省重点实验室（kc1704005，2017TP1018）；湖南省中医药防治眼病与视功能保护工程技术研究中心建设项目（2018TP2008）；湖南省研究生创新项目（CX20190562）。 |
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| Correlation Between Fundus Signs of Type 2 Diabetes and TCM Syndrome Elements |
| LI Xiang,DENG Ying,LI Xinyu,LIAO Linli,PENG Qinghua |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Changsha, Hunan 410208, China;Hunan Provincial Engineering and Technological Research Center for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine and Protecting Visual Function, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To analyze the correlation between fundus signs and traditional Chinese medicine (TCM) syndromes in patients with type 2 diabetes (T2DM). Methods Through cross-sectional surveys and on-site questionnaires, general information and TCM symptoms of T2DM patients were collected, including fundus photographs and optical coherence tomography (OCT) images, and the syndrome was extracted with the help of WF Wenfeng-Ⅲ TCM (assisted) diagnosis and treatment system. Association rules was used to analyze the relationship between TCM syndromes and fundus signs. Results Diffuse edema had the highest correlation with "dampness", "dampness and liver", cystic edema had the highest correlation with "Qi deficiency and kidney and liver"; rigid exudation had the highest correlation with "Qi deficiency and liver", followed by "dampness"; the syndrome element with the highest correlation between bleeding and microangioma was "Qi deficiency and kidney and liver"; macular epithelial membrane was most closely related to "Yang deficiency", followed by "Yang deficiency and liver", "Yang deficiency and kidney". Conclusion Research results suggest that fundus signs are related to certain syndromes:edema is related to Qi deficiency and blood stasis, exudation is related to Qi deficiency and dampness and phlegm accumulation, microangioma and bleeding are related to Qi deficiency and blood stasis, and macular membrane is related to kidney Yang deficiency. |
| Key words: type 2 diabetes diabetic retinopathy fundus signs syndrome factors of traditional Chinese medicine |
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