| 引用本文: |
王国倩,张晋康,喻正科,陈志红,谢洪途.冠心通络胶囊治疗动脉粥样硬化性心血管疾病的研究进展[J].湖南中医药大学学报,2020,40(10):1298-1304[点击复制] |
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| 冠心通络胶囊治疗动脉粥样硬化性心血管疾病的研究进展 |
| 王国倩,张晋康,喻正科,陈志红,谢洪途 |
| (中山大学孙逸仙纪念医院, 广东 广州 510120;湖南省中医药研究院附属医院, 湖南 长沙 410006;中山大学电子与通信工程学院, 广东 广州 510275) |
| 摘要: |
| 冠心通络胶囊是用于治疗动脉粥样硬化性心血管疾病的复方中药制剂，其作用机制可能与扩张冠状动脉、增加冠状动脉血流量、降低心肌耗氧量、降低全血黏度、降低血浆黏度、降低红细胞压积及改善血液黏稠度等因素有关。本文总结了近年来冠心通络胶囊在治疗动脉粥样硬化性心血管疾病作用方面的最新进展，主要从中医认识、药理研究、基础研究和临床研究等方面进行综述，为后续科学研究和临床应用提供参考。 |
| 关键词: 冠心通络胶囊 动脉粥样硬化 心血管疾病 中医认识 药理研究 基础研究 临床研究 |
| DOI：10.3969/j.issn.1674-070X.2020.10.025 |
| 投稿时间：2020-04-09 |
| 基金项目:国家自然科学基金项目（61801510）；湖北省自然科学基金项目（2019CFB263）；湖南省教育厅科研项目（16C1233）。 |
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| Research Progress of Guanxin Tongluo Capsule in the Treatment of Atherosclerotic Cardiovascular Disease |
| WANG Guoqian,ZHANG Jinkang,YU Zhengke,CHEN Zhihong,XIE Hongtu |
| (Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510120, China;The Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha, Hunan 410006, China;School of Electronics and Communication Engineering, Sun Yat-sen University, Guangzhou, Guangdong 510275, China) |
| Abstract: |
| Guanxin Tongluo Capsule is a compound Chinese materia medica preparation for the treatment of the atherosclerotic cardiovascular diseases. Its action mechanism could be related to the expansion of the coronary arteries, increase of the coronary blood flow, reduction of the myocardial oxygen consumption, reduction of the whole blood viscosity, plasma viscosity and hematocrit, and improvement of the blood viscosity of the patients. This paper summarized the latest progress on the role of the Guanxin Tongluo Capsule in treating atherosclerotic cardiovascular disease in recent years mainly from the aspects of traditional Chinese medicine understanding, pharmacological research, basic research and clinical research, which can provide the reference for the follow-up science research and clinical application. |
| Key words: Guanxin Tongluo Capsule atherosclerosis cardiovascular diseases traditional Chinese medicine understanding pharmacological research basic research clinical research |
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