| 引用本文: |
周春言,李琴,王福祖,张玉兰,张文广,宋维海,星媛,庄志毅,贺明元.皮内针法对气阴两虚型干燥综合征患者疗效观察[J].湖南中医药大学学报,2020,40(7):888-891[点击复制] |
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| 皮内针法对气阴两虚型干燥综合征患者疗效观察 |
| 周春言,李琴,王福祖,张玉兰,张文广,宋维海,星媛,庄志毅,贺明元 |
| (青海省中医院风湿病科, 青海 西宁 810000) |
| 摘要: |
| 目的 探讨皮内针法对气阴两虚型干燥综合征患者的疗效。方法 选择本院接诊的气阴两虚型干燥综合征患者79例进行研究，根据治疗方法分为两组，对照组39例行常规西医治疗，观察组40例在对照组基础上加以皮内针治疗。对比两组临床疗效、中医证候积分、口干眼干客观指标、免疫功能、炎症因子。结果 观察组总有效率为82.50%，明显高于对照组的61.54%（P<0.05）；治疗后两组患者中医证候积分明显下降，且观察组低于对照组（P<0.05）；治疗后两组患者唾液流率及Schirmer氏泪液试验结果均明显升高，且观察组高于对照组（P<0.05）；治疗后两组患者IgG、补体C3、补体C4均明显升高，且观察组高于对照组（P<0.05）；治疗后两组患者TNF-α、CRP及IL-6均明显下降，且观察组低于对照组（P<0.05）。结论 皮内针法联合常规西医治疗较单独使用常规西医治疗气阴两虚型干燥综合征患者，可明显提高疗效、改善其中医证候及临床症状、提高免疫功能、降低炎症反应。 |
| 关键词: 干燥综合征 皮内针 气阴两虚 免疫功能 炎症因子 |
| DOI：10.3969/j.issn.1674-070X.2020.07.021 |
| 投稿时间：2019-10-25 |
| 基金项目:青海省中藏医药研究课题项目（2018103）。 |
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| Therapeutic Effect Observation on Intradermal Acupuncture for Patients with Sjogren Syndrome with Deficiency of Qi and Yin |
| ZHOU Chunyan,LI Qin,WANG Fuzu,ZHANG Yulan,ZHANG Wenguang,SONG Weihai,XING Yuan,ZHUANG Zhiyi,HE Mingyuan |
| (Department of Rheumatology, Qinghai Provincial Hospital of Traditional Chinese Medicine, Xining, Qinghai 810000, China) |
| Abstract: |
| Objective To explore the clinical effects of intradermal acupuncture on patients with Sjogren syndrome with deficiency of Qi and Yin. Methods A total of 79 patients with Sjogren syndrome of Qi-Yin deficiency treated in our hospital were selected for study. They were divided into 2 groups according to the treatment methods. 39 cases in the control group were treated with conventional western medicine and 40 cases in the observation group were treated with intradermal acupuncture based on the control group. The clinical efficacy, traditional Chinese medicine (TCM) syndrome scores, objective indicators of dry mouth and dry eye, immune function and inflammatory factors were compared between the 2 groups. Results The total effective rate of the observation group was 82.50%, which was significantly higher than 61.54% of the control group (P<0.05). After treatment, the TCM syndrome scores of the 2 groups of patients decreased significantly, and the observation group was lower than the control group (P<0.05). After treatment, the results of saliva flow rate and Schirmer's tear test increased significantly, and the observation group was higher than the control group (P<0.05). After treatment, the IgG, complement C3, and complement C4 in the 2 groups were significantly increased, and the observation group was higher than the control group (P<0.05). After treatment, the levels of TNF-α, CRP and IL-6 in the 2 groups were significantly decreased, but the observation group was lower than the control group (P<0.05). Conclusion Intradermal acupuncture combined with conventional western medicine treatment can significantly improve the efficacy in the treatment of patients with Sjogren syndrome with Qi and Yin deficiency, significantly improve clinical efficacy, TCM syndromes and clinical symptoms, improve immune function and reduce inflammatory response. |
| Key words: Sjogren's syndrome intradermal acupuncture Qi and Yin deficiency immune function inflammatory factor |
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