| 引用本文: |
刘保松,白明,彭孟凡,刘田园,苗明三.基于中西医临床病症特点的干眼动物模型分析[J].湖南中医药大学学报,2020,40(1):114-116[点击复制] |
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| 基于中西医临床病症特点的干眼动物模型分析 |
| 刘保松,白明,彭孟凡,刘田园,苗明三 |
| (驻马店市中医院, 河南 驻马店 463800;河南中医药大学, 河南 郑州 450046) |
| 摘要: |
| 本文基于临床干眼疾病的中西医诊断标准，对现阶段干眼动物模型与临床病症的吻合情况进行分析与探究，总结干眼模型造模方法及特点，并与临床相关症状及标准进行对比，提出在评判干眼动物模型时应增加表观指标，并确定统一的评价体系，进一步完善和发展现有干眼动物模型。未来重点应放在制备病-证相结合的动物模型，以便为促进干眼的深层次研究提供理论基础。 |
| 关键词: 干眼 临床病症 动物模型 诊断标准 |
| DOI：10.3969/j.issn.1674-070X.2020.01.025 |
| 投稿时间：2018-04-23 |
| 基金项目:国家"十一五"支撑计划课题项目（2008BAI53B09）；国家中医药管理局中医药标准化专项（2017-149-11）；国家国际合作基地（国科外函2016-65）。 |
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| Analysis of Dry Eye Animal Models Based on Clinical Features of Traditional Chinese Medicine and Western Medicine |
| LIU Baosong,BAI Ming,PENG Mengfan,LIU Tianyuan,MIAO Mingsan |
| (Zhumadian Chinese Medicine Hospital, Zhumadian, Henan 463800, China;Henan University of Chinese Medicine, Henan, Zhengzhou 450046, China) |
| Abstract: |
| Based on the clinical diagnostic criteria of traditional Chinese medicine and western medicine in dry eyes, this paper analyzed and explored the current situation of the match between animal models of dry eye and clinical conditions, summarized the methods and characteristics of dry eye modeling, and compared them with clinically relevant symptoms and standards. It is proposed that in the evaluation of dry eye animal models, performance indicators should be added, and a unified evaluation system should be determined to further improve and develop the existing dry eye animal models. In the future, the focus should be on preparing animal models combining disease and syndrome in order to promote provides a theoretical basis for in-depth research on dry eye. |
| Key words: dry eyes clinical disease and syndrome animal model diagnostic criteria |
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