| 引用本文: |
赵碧清,何雨晴,卢辛甜,冯曦,袁志鹰,许光明.黄瓜根化学成分的分离与鉴定[J].湖南中医药大学学报,2019,39(8):1015-1017[点击复制] |
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| 黄瓜根化学成分的分离与鉴定 |
| 赵碧清,何雨晴,卢辛甜,冯曦,袁志鹰,许光明 |
| (湖南中医药大学, 湖南 长沙 410208) |
| 摘要: |
| 目的 研究黄瓜根的化学成分。方法 采用乙醇提取、不同极性溶剂萃取法初步分离，再采用大孔吸附树脂、正相硅胶、反相硅胶（RP-18）、Sephadex LH-20凝胶等柱色谱技术对黄瓜根化学成分进行分离纯化，根据理化性质、波谱数据和文献比对，鉴定出所得化合物的结构。结果 从黄瓜根不同提取物中分离得到8个化合物，分别鉴定为反式对羟基桂皮醛（1）、4-hydroxy-4-（3-oxo-1-butenyl）-3，5，5-trimethylcyclohex-2-en-1-one（2）、loliolide（3）、ligballinol（4）、对甲氧基苯酚（5）、3-吲哚甲醛（6）、3-氨基吲哚（7）、3-吲哚甲酸甲酯（8）。结论 化合物2、3、4、5、7为首次从该植物中分离得到。 |
| 关键词: 黄瓜根 化学成分 结构鉴定 |
| DOI：10.3969/j.issn.1674-070X.2019.08.019 |
| 投稿时间：2019-03-25 |
| 基金项目:湖南省中药饮片标准化及功能工程技术研究中心开放基金资助项目（BG201705）；湖南中医药大学中药学一流学科开放基金项目（2018ZYX01）；湖南中医药大学中药学一流学科项目资助。 |
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| Study on Chemical Constituents of the Roots of Cucumis sativus L. |
| ZHAO Biqing,HE Yuqing,LU Xintian,FENG Xi,YUAN Zhiying,XU Guangming |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Object To Study the chemical constituents of the roots of Cucumis sativus L.. Methods The chromatographic separation and purification of the ethyl acetate and n-butyl alcohol parts of the roots of Cucumis sativus L. were carried out on normal phase silica gel, reversed phase silica gel(RP-18), and Sephadex LH-20 column chromatography, their structures were identified by the analysis of spectral data and chemical properties. Results Eight compounds were obtained at the parts of the ethyl acetate and n-butyl alcohol from the roots of Cucumis sativus L., which were elucidated as trans-p-coumaryl aldehyde(1), 4-hydroxy-4-(3-oxo-1-butenyl)-3,5,5-trimethylcyclohex-2-en-1-one(2), Loliolid(3), ligballinol(4), p-methoxy phenol(5), indole-3-carboxaldehyde(6), 3-amine-1H-indol(7), methyl-3-indolecarboxylate(8). Conclusion Compounds 2, 3, 4, 5, 7 were isolated from this plant for the first time. |
| Key words: the roots of Cucumis sativus L. chemical components structure identification |
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