| 引用本文: |
黄浩,王骁腾,贾佳,洪军.化痰脉通片对冠心病痰瘀互结证患者血脂的影响[J].湖南中医药大学学报,2018,38(11):1312-1315[点击复制] |
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| 化痰脉通片对冠心病痰瘀互结证患者血脂的影响 |
| 黄浩,王骁腾,贾佳,洪军 |
| (新疆医科大学附属中医医院, 新疆 乌鲁木齐 830000) |
| 摘要: |
| 目的 以痰瘀同治为法，治疗冠心病痰瘀互结证患者，观察化痰脉通片的临床疗效及其对血脂的影响。方法 入选符合冠心病痰瘀互结证患者48例，随机分为对照组23例和治疗组25例。对照组采用常规治疗（如阿司匹林肠溶片、他汀类、CCB、ARB或ACEI、β受体阻滞剂、硝酸酯类、血运重建等），治疗组在常规治疗的基础上加化痰脉通片，疗程为6个月。治疗前后测定血脂4项并进行中医证侯积分测评。结果 与对照组比较，治疗组总胆固醇（TC）、低密度脂蛋白（LDL-C）的水平降低，差异有统计学意义（P<0.05）；在中医证候改善上，治疗组积分比对照组下降更多，差异有统计学意义（P<0.05）。结论 化痰脉通片不仅能降低冠心病（痰瘀互结证）患者TC、LDL-C水平，还能改善痰瘀互结情况，减轻病人临床不适症状，提高患者生活质量。 |
| 关键词: 冠心病 痰瘀互结 痰瘀同治 血脂 化痰脉通片 半夏 |
| DOI：10.3969/j.issn.1674-070X.2018.11.021 |
| 投稿时间：2018-09-06 |
| 基金项目:新疆维吾尔自治区科学技术厅资助项目（2014211C099） |
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| Effect of Huatan Maitong Tablet on Blood Lipids in Patients with Intermingled Phlegm and Blood Stasis Syndrome of Coronary Heart Disease |
| HUANG Hao,WANG Xiaoteng,JIA Jia,HONG Jun |
| (Affiliated Traditional Chinese Medicine Hospital, Xinjiang Medical University, Urumqi, Xinjiang 830000, China) |
| Abstract: |
| Objective To observe the clinical efficacy of Huatan Maitong Tablet (co-treatment of phlegm and stasis) and its effect on blood lipids in patients with intermingled phlegm and blood stasis syndrome of coronary heart disease (CHD). Methods Forty-eight patients with intermingled phlegm and blood stasis syndrome of CHD were randomly divided into control group (n=23) and treatment group (n=25). The control group received conventional treatment (such as aspirin enteric-coated tablet, statins, calcium channel blocker, angiotensin receptor blocker, angiotensin-converting enzyme inhibitor, β-receptor blocker, nitrates, and revascularization), and the treatment group was given Huatan Maitong Tablet in addition to the conventional treatment. The course of treatment was 6 months for both groups. Four indices of blood lipids were measured before and after treatment, and traditional Chinese medicine (TCM) syndrome scores were evaluated. Results The levels of total cholesterol (TC) and low-density lipoprotein (LDL-C) in the treatment group were significantly lower than those in the control group (P<0.05). For the improvement in TCM syndromes, the scores decreased more in the treatment group than in the control group (P<0.05). Conclusion Huatan Maitong Tablet can not only reduce the levels of TC and LDL-C in patients with coronary heart disease (intermingled phlegm and blood stasis syndrome), but also relieve the intermingling of phlegm and blood stasis. Therefore, it can reduce the clinical symptoms of patients and improve their quality of life. |
| Key words: coronary heart disease intermingled phlegm and blood stasis co-treatment of phlegm and stasis blood lipids Huatan Maitong Tablet Pinellia ternata |
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