| 引用本文: |
乔亚琴,于舒芃,翟卫春,张久聪,董敏,张小强,于晓辉.儿童幽门螺杆菌感染性相关疾病的研究进展[J].湖南中医药大学学报,2018,38(9):1082-1088[点击复制] |
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| 儿童幽门螺杆菌感染性相关疾病的研究进展 |
| 乔亚琴,于舒芃,翟卫春,张久聪,董敏,张小强,于晓辉 |
| (兰州总医院消化内科, 甘肃 兰州 730050;金昌市中心医院消化内科, 甘肃 金昌 737100;天津中医药大学, 天津 300000) |
| 摘要: |
| 幽门螺杆菌（helicobacter pylori，Hp）被列为一级致癌因子，是慢性胃病的主要致病菌。该菌不仅与慢性胃炎、消化性溃疡、胃癌等多种胃肠道疾病的发病密切相关，还可能参与了多种胃肠道外疾病的发生，如缺铁性贫血、过敏性紫癜、慢性荨麻疹、偏头痛、帕金森病等。Hp感染了全球半数以上的人口，50%以上的成人Hp感染性相关疾病患者都是在儿童期感染了Hp，而未得到及时根治所致，故儿童是受Hp影响最危险的人群。本文就儿童Hp感染的流行病学、相关性疾病及诊治等方面予以综述。 |
| 关键词: 幽门螺杆菌 感染 儿童 流行病学 诊断检测 |
| DOI：10.3969/j.issn.1674-070X.2018.09.026 |
| 投稿时间：2018-03-31 |
| 基金项目:全军医药卫生科研基金（CLZ14JB01）。 |
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| Research Progress in Helicobacter pylori Infection-Related Diseases in Children |
| QIAO Yaqin,YU Shupeng,ZHAI Weichun,ZHANG Jiucong,DONG Min,ZHANG Xiaoqiang,YU Xiaohui |
| (Department of Gastroenterology, General Hospital of Lanzhou Military Command, Lanzhou, Gansu 730050, China;Department of Gastroenterology, Jinchang Central Hospital, Jinchang, Gansu 737100, China;Tianjin University of Traditional Chinese Medicine, Tianjin 300000, China) |
| Abstract: |
| Helicobacter pylori(Hp) has been recognized as a class I carcinogen, as well as the major pathogen for chronic gastric diseases. Hp is closely associated with the development of many gastrointestinal diseases, including chronic gastritis, peptic ulcer, and gastric cancer, as well as various extra-gastrointestinal diseases, such as iron deficiency anemia, allergic purpura, chronic urticaria, migraine, and Parkinson's disease. Hp has infected more than half of the world's population. More than 50% of adult patients developed Hp infection-related diseases due to Hp infections dating back to childhood which were not thoroughly cured. Therefore, children are the most vulnerable population to Hp infection. This article is a review on Hp infection in children from the perspectives of epidemiology, related diseases, and diagnosis and treatment. |
| Key words: Helicobacter pylori infection child epidemiology diagnostic test |
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