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王净净,刘宇哲.自拟健脑安神汤治疗原发性失眠的临床观察[J].湖南中医药大学学报,2017,37(4):409-412[点击复制] |
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自拟健脑安神汤治疗原发性失眠的临床观察 |
王净净,刘宇哲 |
(湖南中医药大学中西医结合学院, 湖南 长沙 410208;湖南中医药大学2014级台籍硕士研究生, 湖南 长沙 410208) |
摘要: |
目的 观察健脑安神汤治疗原发性失眠的临床疗效。方法 将65例原发性失眠患者随机分为观察组35例(健脑安神汤)及对照组30例(酸枣仁汤),疗程均为1周,并以匹兹堡睡眠质量指数(PSQI)、简易睡眠个人信念与态度量表(DBAS-16)、简易智力状况检查法(MMSE)、中医临床证候计分表,4种量表比较临床疗效。结果 经治疗后观察组总有效率78.8%,对照组总有效率63.6%;观察组的PSQI和中医证候疗效优于对照组,差异有统计学意义(P<0.05);观察组在改善DBAS-16和MMSE积分方面均明显优于对照组,差异有统计学意义(P<0.05);两组均未见明显不良反应。结论 健脑安神汤治疗原发性失眠疗效显著,安全性好,值得临床推广应用。 |
关键词: 原发性失眠 健脑安神汤 临床疗效 |
DOI:10.3969/j.issn.1674-070X.2017.04.018 |
投稿时间:2016-06-27 |
基金项目:全国名老中医药专家传承工作室建设项目[国中医药人发(2016)42号] |
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Clinical Efficacy of Jiannao Anshen Decoction on Treatment of Primary Insomnia |
WANG Jingjing,LIU Yuzhe |
(College of Combination of Traditional Chinese Medicine and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Postgraduate in Grade 2014, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
Abstract: |
Objective To observe the clinical effect of Jiannao Anshen decoction in treatment of primary insomnia. Methods The 65 patients with primary insomnia were randomly divided into the observation group (Jiannao Anshen decoction), 35 cases, and control group (Suanzaoren decoction), 30 cases. The curative course was for 1 week. The Pittsburgh sleep quality index (PSQI), simple sleep personal beliefs and attitudes about weight table (DBAS-16), mini mental state examination check (MMSE), and TCM syndromes score table were evaluated for the clinical effect. Results The total efficacy rate of the observation group was 78.8%, and the control group was for 63.6%. The curative effects of PSQI and TCM syndromes in observation group were better than control group after treatment, the differences were statistically significant (P<0.05). The curative effects of DBAS-16 and MMSE in observation group were better than control group after treatment, the differences were statistically significant (P<0.05), there was no obvious adverse reaction in the two groups. Conclusion The effect of Jiannao Anshen decoction is remarkable and safe in the treatment of primary insomnia. So it is worthy of clinical application. |
Key words: primary insomnia Jiannao Anshen decoction clinical efficacy |
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