| 引用本文: |
谢梦洲,贺佐梅,周小青,吴正治.唾液检测的应用进展[J].湖南中医药大学学报,2016,36(2):76-80[点击复制] |
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| 唾液检测的应用进展 |
| 谢梦洲,贺佐梅,周小青,吴正治 |
| (湖南中医药大学中医诊断国家重点学科, 湖南2011数字中医药协同创新中心, 湖南 长沙 410007;抗肿瘤中药创制技术湖南省工程研究中心, 湖南 长沙 410007;湖南中医药大学中医诊断国家重点学科, 湖南2011数字中医药协同创新中心, 湖南 长沙 410007;广东医学院附属福田医院, 广东 深圳 518033;深圳大学第一附属医院, 广东 深圳 518035) |
| 摘要: |
| 唾液检测是一种近年兴起的、研究比较热门的医学检查方法。唾液中存在反映全身健康状况的生物标志物，其蕴含着大量的生物信息。与尿液标本相比，唾液具有可实时采样的优点。与血清标本相比，唾液采集安全方便，无创伤，无血源性疾病传播的危险，患者无痛苦，易于接受。唾液检测正成为当前无创检验领域最具潜力和应用前景的研究热点。总结回顾唾液检测技术的发展现状，及其在疾病诊治、药物水平检测、心理学研究、法医取证、职业和环境医学及中医辨证客观化研究方面的进展，可为进一步研究提供参考。 |
| 关键词: 唾液检测 诊断 生物标志物 |
| DOI：10.3969/j.issn.1674-070X.2016.02.021 |
| 投稿时间：2015-01-24 |
| 基金项目:国家自然科学基金资助项目（81273665）；湖南中医药大学中医诊断国家重点学科开放基金项目（201401）；湖南省2011数字中医药协同创新中心。 |
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| Advance on the Application of Salivary Diagnostics |
| XIE Mengzhou,HE Zuomei,ZHOU Xiaoqing,WU Zhengzhi |
| (2011 Collaborative Innovation Center of Digital Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Hunan Engineering Research Center for the Technology of Creation & Mannufacture of Chinese Medicine for Anti-tumor, Changsha, Hunan 410007, China;2011 Collaborative Innovation Center of Digital Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;The Futian Hospital Affiliated to Guangdong Medical Institute, Shenzhen, Guangdong 518033, China;The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518020, China) |
| Abstract: |
| Saliva test is a kind of research popular in recent years. The biomarkers in saliva could reflect systemic health condition, it contains abundant bioinformations. Compared with urine specimen, saliva has the advantages of real-time sampling. Compared with the serum specimens, saliva collection is safe, noninvasive, no risk of spreading the blood-borne diseases, patients are easy to accept. Saliva test is becoming the most potential and application prospect in current noninvasive test field. Here it will be elaborated on the research progress in clinical diagnosis and therapeutic application, drug level monitoring, psychological research, forensics, etc. of saliva testing, to provide references for further study. |
| Key words: saliva testing diagnosis biomarkers |
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