| 引用本文: |
席建元;陶璇;李小鹏;祁林;谢明峰;.银屑平丸治疗寻常型银屑病的疗效及对血清IL-8的影响[J].湖南中医药大学学报,2012,32(1):51-53[点击复制] |
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| 银屑平丸治疗寻常型银屑病的疗效及对血清IL-8的影响 |
| 席建元;陶璇;李小鹏;祁林;谢明峰; |
| (湖南中医药大学第一附属医院皮肤科; 宁乡县人民医院) |
| 摘要: |
| 目的观察银屑平丸治疗寻常型银屑病血热证的临床疗效及其对血清IL-8含量的影响。方法将70例患者随机分为两组,治疗组口服银屑平丸,对照组口服复方青黛丸,疗程均为8周,同时设立20名健康体检者作对照。计算治疗前后PASI(银屑病面积和严重程度指数)评分及检测外周血血清IL-8含量。结果两组治疗后PASI积分均有明显下降(P<0.01),治疗组下降较对照组更明显(P<0.01)。两组患者治疗前血清IL-8含量明显高于正常人(P<0.01),治疗后两组血清IL-8含量明显下降(P<0.01),治疗组较对照组更明显(P<0.01)。结论银屑平丸能同时降低寻常型银屑病的PASI积分及血清IL-8含量,临床疗效确切。 |
| 关键词: 银屑病 中药治疗 银屑平丸 血热证 白细胞介素8 |
| DOI： |
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| Curative effects of Yinxieping pill on psoriasis and effects of it on serum IL-8 |
| XI Jian-yuan1,TAO Xuan2,LI Xiao-peng1,QI Lin1,XIE Ming-feng1 |
| (1.First Affiliated Hospital,TCM University of Hunan,Changsha,Hunan 410007,China; 2.People’s Hospital of Ningxiang,Ningxiang,Hunan 410600,China) |
| Abstract: |
| (Abstract〕 Objective To study the efFec is of Yinxieping pill on psoriasis vulgaris in
blood-heat syndrome and its impacts
on IL-8
in serum
Methods 70 patients with blood-heat
syndrome of psoriasis vulgaris were
randomly divided into treatment
group and control group.
the patients in treatment group were treated with Yinxieping pill and in control group with Compound
Qingdai pill, the therapeutic course was 8 weeks in both. In addition, 20 healthy volunteers were
selected in control group. Before and after treatment, PASI score was calculated and peripheral
blood serum IL-8 content was measured. Results PASI scores were significantly decreased after
treatment in treatment group and control group (P<0.01, P<0.01), and the results in treatment group was
more
significant than that in control group (P <0.01). Serum IL -8
was
also significantly decreased after treatment in
both groups(P<0.01,P<0.01),and the changes in treatment group
were also more significant than that in control group(P <0.01).
Conclusion Yinxieping pill can decrease the IL-8
level and PASI score in blood -heat syndrome of psoriasis vulgaris.It has obvious curative effects |
| Key words: (Key words〕 psoriasis treatment of Chinese medicine Yinxieping pill blood-heat syndrome interleukin-8(IL-8) |
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