| 引用本文: |
黎铭玉,周巍,周兰,艾坤,刘梨,刘密.基于中医阴阳理论探讨针灸对细胞自噬的调节作用及意义[J].湖南中医药大学学报,2020,40(11):1427-1431[点击复制] |
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| 基于中医阴阳理论探讨针灸对细胞自噬的调节作用及意义 |
| 黎铭玉,周巍,周兰,艾坤,刘梨,刘密 |
| (湖南中医药大学针灸推拿学院, 湖南 长沙 410208;湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学针灸推拿学院, 湖南 长沙 410208;浏阳市中医医院, 湖南 浏阳 410300) |
| 摘要: |
| 细胞自噬是近年来生物医学领域研究的热点问题，自噬既是人体诸多生理机能的参与者，又是多种疾病发展变化的风险因子。阴阳理论是中医最基本的理论学说之一，其追求阴阳平和的思想与自噬调控细胞内环境稳态的作用不谋而合。针灸可通过调和阴阳达到治愈疾病的目的，也能调控自噬的相关信号通路介导自噬的发生发展。本文尝试以中医阴阳理论为基础，探讨针灸对自噬的调节作用，为更深入地了解针灸与自噬的关系提供理论依据。 |
| 关键词: 细胞自噬 针灸 阴阳理论 内环境稳态 |
| DOI：10.3969/j.issn.1674-070X.2020.11.025 |
| 投稿时间：2020-05-13 |
| 基金项目:国家自然科学基金项目（81804204）；湖南省自然科学基金项目（2018JJ2295）；湖南省高校创新平台开放基金项目（18K066）；长沙市科技计划项目（kq1801184）；湖南省科技人才托举工程项目（2019TJ-Q04）；湖南省“芙蓉学者奖励计划”（湘教通〔2020〕58号）；湖南省高层次卫生人才“225”工程培养项目（湘卫函〔2019〕196号）；湖南省121创新人才培养工程（湘人社函〔2019〕192号）。 |
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| Modulation and Significance of Acupuncture on Autophagy Based on the Yin-Yang Theory of Traditional Chinese Medicine |
| LI Mingyu,ZHOU Wei,ZHOU Lan,AI Kun,LIU Li,LIU Mi |
| (School of Acupuncture, Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;School of Acupuncture, Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Liuyang Hospital of Traditional Chinese Medicine, Liuyang, Hunan 410300, China) |
| Abstract: |
| Autophagy is a hot topic in biomedical field in recent years. Autophagy is not only a participant in many physiological functions of human, but also a risk factor for many diseases' development. The Yin-Yang theory is one of the basic theories of traditional Chinese medicine, and its pursuit of peace of Yin and Yang coincides with the role of autophagy in regulating the homeostasis of intracellular environment. Acupuncture can cure diseases by reconciling Yin and Yang, and it can also regulate the related signal pathway of autophagy to mediate the occurrence and development of autophagy. This paper attempted to explore the regulatory effect of acupuncture on autophagy based on the "Yin-Yang theory" of traditional Chinese medicine, so as to provide theoretical basis for better understanding of the relationship between acupuncture and autophagy. |
| Key words: autophagy acupuncture Yin-Yang theory internal environment homeostasis |
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