| 引用本文: |
吴淑辉,朱明芳,张曦,刘银格,张娟娟.基于数据挖掘探讨朱明芳教授治疗寻常痤疮的用药规律[J].湖南中医药大学学报,2020,40(9):1142-1146[点击复制] |
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| 基于数据挖掘探讨朱明芳教授治疗寻常痤疮的用药规律 |
| 吴淑辉,朱明芳,张曦,刘银格,张娟娟 |
| (湖南中医药大学第二附属医院, 湖南 长沙 410005) |
| 摘要: |
| 目的 探讨朱明芳教授治疗寻常痤疮的用药规律。方法 收集朱明芳教授门诊2013年6月至2016年10月303例寻常痤疮首诊处方，利用数据挖掘分析寻常痤疮主要症状、药物频次及症状药物关联度等。结果 症状频次大于20%者为皮疹、口干欲饮、面油腻、失眠多梦、便秘；中药使用频次前5位由高到低依次为甘草、白芷、薄荷、夏枯草、马鞭草；通过聚类分析得出治疗上关系密切的药对12个。结论 朱明芳教授认为寻常痤疮病性多实，病位多在肺、脾、胃，多以湿热为见，治宜清热祛湿为主，同时善用白芷及皮类药物治疗。 |
| 关键词: 寻常痤疮 数据挖掘 用药规律 朱明芳 |
| DOI：10.3969/j.issn.1674-070X.2020.09.019 |
| 投稿时间：2020-03-25 |
| 基金项目:湖南省教育厅科学研究项目（18A212）；湖南省临床医疗技术创新引导项目（2018SK51102）；湖南省研究生科研创新项目计划（CX2018B501）；湖南省高层次卫生人才“225”工程培养项目。 |
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| Medication Laws of Professor ZHU Mingfang in Treating Acne Vulgaris Based on Data Mining |
| WU Shuhui,ZHU Mingfang,ZHANG Xi,LIU Yin'ge,ZHANG Juanjuan |
| (The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410005, China) |
| Abstract: |
| Objective To explore the medication laws of professor ZHU Mingfang in treating acne vulgaris. Methods A total of 303 out-patient first-visit prescriptions of acne vulgaris from June 2013 to October 2016 were collected. Data mining was used to analyze the main symptoms of acne vulgaris, drug frequency, and symptomatic drug association. Results Symptoms with a frequency of more than 20% were skin rash, dry mouth and willing to drink, greasy face, insomnia and dreaminess, and constipation; the top 5 Chinese materia medica in descending order were Radix Glycyrrhizae, Radix Angelicae Dahuricae, Herba Menthae, Spica Prunellae, and Herba Verbenae; Clustering analysis showed that 12 drug pairs were closely related in treatment. Conclusion Professor ZHU Mingfang considers the nature of acne vulgaris is excess, and the location is in the lung, spleen and stomach, and usually manifested as dampness heat. Therefore, the treatment should clear heat and remove dampness and be good at using Radix Angelicae Dahuricae and peel herbs in the treatment of acne vulgaris. |
| Key words: acne vulgaris data mining medication laws ZHU Mingfang |
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