| 引用本文: |
张书萌,张湘卓,曾雪芹,周俊鹏,张梦雪,李仙福,江雨洁,李杰.柴胡疏肝散加减治疗冠心病心绞痛疗效的Meta分析[J].湖南中医药大学学报,2020,40(7):867-871[点击复制] |
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| 柴胡疏肝散加减治疗冠心病心绞痛疗效的Meta分析 |
| 张书萌,张湘卓,曾雪芹,周俊鹏,张梦雪,李仙福,江雨洁,李杰 |
| (湖南中医药大学, 湖南 长沙 410208) |
| 摘要: |
| 目的 运用Meta分析方法对柴胡疏肝散加减治疗冠心病心绞痛的疗效进行评价。方法 检索中国知网数据库、维普期刊全文数据库、万方数据库、中国生物医学文献服务系统及PubMed，查找有关柴胡疏肝散治疗冠心病心绞痛的临床随机对照研究，检索期限均从建库至2019年11月15日，按Cochrane系统评价方法对纳入资料进行质量评估，采用RevMan 5.3软件进行Meta分析。结果 共纳入12篇随机对照试验，全部为中文文献，共940例患者。Meta分析结果显示，柴胡疏肝散加减治疗在心绞痛疗效与心电图改善方面均优于对照组，差异具有统计学意义，分别为[OR=4.55，95% Cl（3.02，6.84），P<0.000 01]与[OR=3.27，95% Cl（2.22，4.82），P<0.000 01]。结论 柴胡疏肝散加减对冠心病心绞痛患者心绞痛及心电图改善具有较好的疗效。但由于纳入文献数量较少，还需要更多大样本研究来予以证实。 |
| 关键词: 冠心病心绞痛 柴胡疏肝散 系统评价 Meta分析 |
| DOI：10.3969/j.issn.1674-070X.2020.07.016 |
| 投稿时间：2019-09-28 |
| 基金项目:国家自然科学基金项目（81673963，81874375）；湖南省研究生科研创新项目（2018CX63）；湖南省教育厅重点项目（16A160）；湖南省教育厅科研项目重点项目（60011120）；湖南中医药大学中西医结合一流学科开放基金项目（2018ZXYJH23）。 |
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| Meta-Analysis of the Efficacy of Modified Chaihu Shugan Powder in the Treatment of Angina Pectoris |
| ZHANG Shumeng,ZHANG Xiangzhuo,ZENG Xueqin,ZHOU Junpeng,ZHANG Mengxue,LI Xianfu,JIANG Yujie,LI Jie |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To evaluate the efficacy of modified Chaihu Shugan Powder in the treatment of angina pectoris by meta-analysis. Methods CNKI, VIP, Wanfang Database, SinoMed and PubMed were searched for clinical randomized controlled studies on Chaihu Shugan Powder in the treatment of angina pectoris. The search period was from the establishment of the database to November 15, 2019. The quality of the included data was evaluated according to the Cochrane systematic review method, and the meta-analysis was performed using RevMan 5.3 software. Results A total of 12 randomized controlled trials written in Chinese were included with a total of 940 patients. Meta-analysis showed that modified Chaihu Shugan Powder was better than the control group in the treatment of angina pectoris and electrocardiogram improvement, and the difference was statistically significant[OR=4.55, 95%Cl (3.02, 6.84), P<0.000 01] and[OR=3.27, 95%Cl (2.22, 4.82), P<0.000 01]. Conclusion Modified Chaihu Shugan Powder has a good effect on the treatment of angina pectoris and electrocardiogram improvement. However, the quantity of the included literature is low, and more high-quality research is needed to confirm it. |
| Key words: angina pectoris Chaihu Shugan Powder systematic review Meta-analysis |
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