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张欣颖,孙林梅,苏红波,梁靖华.214例肛周脓肿患者脓液细菌培养及耐药性分析[J].湖南中医药大学学报,2019,39(10):1271-1274[点击复制] |
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| 214例肛周脓肿患者脓液细菌培养及耐药性分析 |
| 张欣颖,孙林梅,苏红波,梁靖华 |
| (陕西中医药大学, 陕西 咸阳 712046;陕西中医药大学附属西安市中医医院, 陕西 西安 710021;深圳市中医肛肠医院(福田), 广东 深圳 518000) |
| 摘要: |
| 目的 通过对肛周脓肿患者脓液细菌培养及相关致病菌药敏试验分析，指导临床合理应用抗生素，降低耐药率。方法 回顾性整理、统计、分析西安市中医医院肛肠科2018年1月1日-2018年12月31日收住入院的260例肛周脓肿患者脓液共分离出217株细菌。结果 260例微生物检验报告中，未发现细菌生长46例，细菌生长214例，其中两种细菌生长3例，一种细菌生长211例。214例细菌生长标本中革兰氏阳性菌为14株，占6.45%，革兰氏阴性菌203株，占93.55%。检出最多的致病菌是大肠埃希菌，共检出152株，占70.05%；其次是肺炎克雷伯杆菌，共检出31株，占14.29%。结论 革兰氏阴性菌是肛周脓肿的主要致病菌，以大肠埃希菌、肺炎克雷伯菌为主；革兰氏阴性菌对β内酰胺类有较高耐药性；致病菌的耐药现象严重，故医院应加强细菌耐药性监测，合理使用抗菌药物。 |
| 关键词: 肛周脓肿 细菌培养 药敏分析 大肠埃希菌 β-内酰胺酶 |
| DOI：10.3969/j.issn.1674-070X.2019.10.022 |
| 投稿时间：2019-06-26 |
| 基金项目:陕西省中医管理局中医药科研课题（LCPT062）。 |
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| Bacterial Culture of Pus and Drug Resistance Analysis in 214 Patients with Perianal Abscess |
| ZHANG Xinying,SUN Linmei,SU Hongbo,LIANG Jinghua |
| (Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China;Xi'an Hospital of Traditional Chinese Medicine, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi 710021, China;Shenzhen TCM Anorectal Hospital(Futian), Shenzhen, Guangdong 518000, China) |
| Abstract: |
| Objective To analyze bacterial culture of pus and drug sensitivity test of related pathogenic bacteria in perianal abscess patients, so as to guide rational application of antibiotics in clinical practice and reduce the rate of drug resistance. Methods A total of 217 strains of bacteria were isolated from 260 patients with perianal abscess admitted to Anorectal Department in Xi'an Hospital of Traditional Chinese Medicine from January 1, 2018 to December 31, 2018. And they were performed retrospective collation, statistics and analysis. Results In 260 reports of microbiological test, 46 cases of bacterial growth were "not found" and 214 cases of bacterial growth were "found", in which 3 cases were growth with 2 kinds of bacteria, and 211 cases were growth with 1 kind of bacteria. Among the 214 cases with bacterial growth, there were 14 strains of Gram-positive bacteria accounting for 6.45%, and 203 strains of Gram-negative bacteria accounting for 93.55%. The most pathogenic bacteria detected were Escherichia coli, which were 152 strains, accounting for 70.05%. The followed were Klebsiella pneumoniae, and a total of 31 strains were detected, accounting for 14.29%. Conclusion Gram-negative bacteria are the main pathogenic bacteria of perianal abscess, mainly Escherichia coli and Klebsiella pneumoniae. Gram-negative bacteria have higher resistance to β-lactamase. The drug resistance of pathogenic bacteria is serious, so hospitals should strengthen the monitoring of bacterial resistance and use antimicrobial drugs rationally. |
| Key words: perianal abscess bacterial culture drug sensitivity analysis Escherichia coli β-lactamase |
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