| 引用本文: |
朱建平,谢梦洲,邓文祥,冯楚雄,向茗.黄精酸奶降脂作用的实验研究[J].湖南中医药大学学报,2017,37(7):805-808[点击复制] |
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| 黄精酸奶降脂作用的实验研究 |
| 朱建平,谢梦洲,邓文祥,冯楚雄,向茗 |
| (湖南中医药大学, 湖南 长沙 410208;中医诊断学湖南省重点实验室, 湖南 长沙 410208;湖南省药食同源功能性食品工程技术研究中心, 湖南 长沙 410208) |
| 摘要: |
| 目的 探讨黄精酸奶对摄食高脂饲料大鼠的降脂作用。方法 SD大鼠64只，雌雄各半，随机为正常组，高脂血症模型组，黄精组，普通酸奶组，阿托伐他汀组，黄精酸奶高、中、低剂量组。正常组喂基础饲料，其余各组喂养高脂饲料并给予相应的药物灌胃，每天1次，连续8周。分别在实验4周、8周后，眼眶釆血，检测血中三酰甘油（TG）、总胆固醇（TG）、低密度脂蛋白（LDL-C）、高密度脂蛋白（HDL-C）水平。结果 4周、8周后测试结果都显示，与模型组相比，黄精酸奶可降低TC、TG、LDL-C，升高HDL-C（P<0.05或P<0.01），黄精酸奶组的降脂作用优于黄精组、普通酸奶组（P<0.05或P<0.01）。结论 黄精酸奶具有降脂作用，其效果优于单纯食用黄精或酸奶。 |
| 关键词: 黄精酸奶 降脂 甘油三脂 总胆固醇 |
| DOI：10.3969/j.issn.1674-070X.2017.07.029 |
| 投稿时间：2016-09-16 |
| 基金项目:湖南省科技厅重点项目基金资助（2016SK2034）；长沙市科技局一般项目基金资助（kq1602018）；湖南中医药大学中医诊断学国家重点学科开放基金资助（2015ZYZD25）。 |
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| Study of Polygonatum Yoghurt on Lipid-Lowering |
| ZHU Jianping,XIE Mengzhou,DENG Wenxiang,FENG Chuxiong,XIANG Ming |
| (Hunan University of Chinese Medicine, Changsha, Hunan 410208, China;Hunan Province Key Laboratory of TCM Diagnostics, Changsha, Hunan 410208, China;Hunan Engineering Research Center of Medicine and Food Homology Functional Food, Changsha, Hunan 410208, China) |
| Abstract: |
| Objective To investigate the effect of Polygonatum yoghurt on the lipid-lowering of high fat diet rats. Methods 64 SD rats with half males and half females were randomly divided into normal control group, hyperlipidemia model group, Polygonatum group, regular yogurt group, atorvastatin group, high dose of Polygonatum yogurt group, middle dose of Polygonatum yogurt group, low dose group of Polygonatum yogurt. The normal group were fed with basic diet, the other groups were fed with high fat diet and given the corresponding medicine, once a day for 8 weeks. After 4 weeks and 8 weeks, the orbital blood samples were collected to detect the levels of three acylglycerin (TG), total cholesterol (TC), low density lipoprotein (LDL-C) and high density lipoprotein (HDL-C). Results The test results of 4 weeks and 8 weeks show that, compared with the model group, the Polygonatum yoghurt could reduce TC, TG, LDL-C, HDL-C, the effect of the Polygonatum yoghurt group is better than the Polygonatum group and the regular yogurt group (P<0.05 or P<0.01). Conclusion The effect of Polygonatum yoghurt in lipid-lowering is better than that of the Polygonatum or regular yoghurt. |
| Key words: Polygonatum yoghurt lipid lowering triacylglycerol total cholesterol |
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