| 引用本文: |
熊静,周振峰,吴婷.龙胆通窍丸对湿热型慢性鼻窦炎抗炎效应的临床研究[J].湖南中医药大学学报,2016,36(12):34-36[点击复制] |
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| 龙胆通窍丸对湿热型慢性鼻窦炎抗炎效应的临床研究 |
| 熊静,周振峰,吴婷 |
| (湖南中医药大学附属岳阳医院, 湖南 岳阳 414000) |
| 摘要: |
| 目的 观察龙胆通窍丸治疗湿热型慢性鼻窦炎的临床疗效。方法 选择湿热型慢性鼻窦炎患者80例，随机分为治疗组与对照组各40例；治疗组以龙胆通窍丸口服，对照组采用西医常规治疗。疗程4周。观察两组治疗前后相关炎性细胞因子血清白介素-6（IL-6）、血清白介素-8（ IL-8）变化及临床疗效评分。结果 治疗后两组VAS、Lund-Kennedy评分均有不同程度降低﹙P<0.01），且治疗组下降更显著（P<0.05）；治疗后两组血清IL-6和IL-8水平明显下降（P<0.01），且治疗组下降更显著（P<0.01）。结论 龙胆通窍丸能显著提高湿热型慢性鼻窦炎患者的临床疗效，其作用优于常规西药治疗。 |
| 关键词: 慢性鼻窦炎 龙胆通窍丸 湿热蕴结 IL-6 IL-8 临床观察 |
| DOI：10.3969/j.issn.1674-070X.2016.12.009 |
| 投稿时间：2016-02-05 |
| 基金项目:湖南省科技厅科技计划项目（2013FJ3021）；湖南省中医药管理局科技项目（2012105）。 |
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| Clinical Study of the Anti-inflammation of Longdan Tongqiao Pills on Patients with Damp Heat Type Chronic Nasosinusitis |
| XIONG Jing,ZHOU Zhenfeng,WU Ting |
| (Yueyang Affiliated Hospital of Hunan University of Chinese Medicine, Yueyang, Hunan 414000, China) |
| Abstract: |
| Objective To observe the clinical effect of Longdan Tongqiao pills on patients with damp heat type chronic nasosinusitis. Methods The 80 cases of damp heat type chronic sinusitis patients were randomly divided into treatment group and control group, 40 cases in each group. The treatment group was taken with Longdan Tongqiao pill orally, the control group was treated with routine Western medicine, the course was for 4 weeks. The changes of IL-6 and IL-8 and clinical effect in the two groups before and after treatment were observed. Results After treatment, the Lund-Kennedy and VAS scores of the two groups were decreased significantly (P<0.01), and the derease degree in treatment group was more obvious (P<0.05). The levels of IL-6 and IL-8 were decined significantly (P<0.01), and the levels of tretment group were lower (P<0.01). Conclusion Longdan Tongqiao pills can significantly improve the clinical effect of patients with damp heat type chronic nasosinusitis and its effect is better than the Western medicine. |
| Key words: chronic nasosinusitis Longdan Tongqiao pills accumulation of dampness IL-6 IL-8 clinical observation |
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